Diol modified Silica Gel on Glass 200um 10x10cm (25 plates) P124077

The separation mechanism of cellulose is via partition chromatography.  It is suitable for separation of amino acids, carbohydrates, nucleic acids and other hydrophilic materials.  It is coated without a binder but produces a hard surface that can be written upon.  Common mobile phases are compatible from non-polar organic to fully aqueous systems.  Since it is an organic adsorbent, it is not compatible with aggressive general visualization techniques such as sulfuric acid charring.  Layers are available with and without a UV254 fluorescent indicator.

Avicel is a refined form of cellulose known as microcrystalline cellulose.  This means it is not fibrous as natural cellulose is, but is more of a discrete particle.  It gives superior separation versus native cellulose because diffusion along the length of the fiber is eliminated.  Avicel also has far fewer impurities than fibrous cellulose which results in a cleaner solvent front.